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Immune System/Infections


If you are interested in hearing more about one or more of the studies listed below, and you are already a Registry participant, please contact the Research Participant Registry at 1-866-438-8230 or via e-mail researchregistry@hs.pitt.edu.

ACTG A5320 PRO14010146
Have you been in a Hepatitis C treatment research study within the past year? If so, you may be eligible to participate in a study where your experience can help researchers develop better ways to treat Hepatitis C. Study visits are twice a year, plus a visit before starting any new Hepatitis C treatment. No medications are provided by this study. Parking/travel-related expenses reimbursed.

ACTG A5314 PRO13090071
Are you at least 40 years of age? Are you HIV-1 positive? People who have an undetectable HIV viral load while on HIV medications for the past 6 months, have a CD4 cell count of at least 400, and have active heart disease or are at risk for heart disease may be eligible to participate in this study that will look at the effects of a medication on inflammation and heart health in those with HIV.

Testing Methods to Screen HIV-positive Women for Predictors of Anal Cancer PRO13110121
Are you a woman who is HIV-infected? If so, you may be eligible to participate in a study to find the best way to screen for anal cancer in HIV-positive women. Participation in this study includes 5 study visits, and participants may be in the study for up to 2 years. Participants will be compensated.

Rifaximin and HIV PRO13060212
Are you infected with HIV, taking anti-retroviral drugs, and have a very low HIV-1 RNA viral load (the amount of HIV in your blood)? If so, you may be eligible to participate in a study to see if rifaximin, an antibiotic that works in the intestines, can reduce bacteria-related inflammation in people with HIV. Participation will last about 16-18 weeks. Compensation is provided.

ENT Research – Ragweed Study PRO13040368A
Do you have ragweed allergy? Are you a relatively healthy adult between the ages of 18 and 50? If so, you may be eligible to participate in a study to determine if allergic rhinitis (nasal allergy) increases the rate of blood-flow in the lining of the middle ear. This study requires three visits to Children’s Hospital of Pittsburgh. Compensation provided.

ENT Research – Healthy Volunteers PRO13040386B
Are you a healthy adult between the ages of 18 and 50? If so, you may be eligible to participate in a study to determine if allergic rhinitis (nasal allergy) increases the rate of blood-flow in the lining of the middle ear. Participants must have no chronic conditions or any known allergies. This study requires two visits to Children’s Hospital of Pittsburgh. Compensation provided.

CHIC II Study PRO11120183
Are you a generally healthy woman between the ages of 18 and 34 years old who has regular periods? If so, and if you are not pregnant or currently using hormones for birth control, you may be eligible to participate in a study to better understand how birth control affects the immune cells within the reproductive tract. Compensation is provided.

HIV Prevention Research Registry PRO11110371
Are you interested in learning about HIV prevention research studies taking place at the University of Pittsburgh and UPMC? If so, you can join the HIV Prevention Research Registry. HIV prevention registry members may be contacted by registry staff members about studies for which they appear to qualify. Eligible participants are ages 18 and older.

ACTG A5308 PRO12100377
Are you age 18 or older and HIV-infected? Has your viral load been less than 500 for the past 2 years? If so, and if you have never taken HIV medications, you may be eligible to participate in a study to see if taking HIV medication reduces immune activation in people who have HIV but show no symptoms. All participants will receive Complera through the study for 1-2 years.

ACTG A5286 PRO11020001
Are you HIV positive and between the ages of 18 and 65? If so, you may be eligible to participate in a study to see whether a certain drug prevents the persistent inflammation that is present in many people with HIV. Participants must have been taking anti-HIV medications for about 2 years or longer, have had an undetectable viral load for the past year, and have a low white blood cell count.

MTN-017 PRO12080047
Are you a HIV-negative man or transgender woman who is age 18 or older? Have you had at least one experience of receptive anal sex in the last 90 days? If so, you may be eligible to participate in a study that is looking at the safety and acceptability of Truvada tablets and tenofovir microbicide gel. Participation lasts approximately 8 months and involves 10 study visits. Compensation provided.

Feel My Best research study PRO09020289
Do you have lupus? Are you experiencing low mood, stress or loss of interest in activities? If so, you may be eligible to participate in study that seeks to see how useful Supportive Counseling and Mind-Body Skills Training are for improving mood and stress symptoms in individuals with Systemic Lupus Erythematosus. Compensation provided.

HPTN-069 - NEXT-PrEP PRO11100727
Are you at least 18 years of age, HIV-negative and a man who has sex with men? If so, you may be eligible to participate in the NEXT PrEP study which is looking at the safety and tolerability of 3 approved anti-HIV medicines being investigated for future use to prevent HIV transmission. Participation lasts one year and includes 11 study visits. Participants will be compensated.

MICL Protocol PRO10010417
Are you between the ages of 18 and 65? Are you HIV-negative OR HIV-positive? Are you willing to provide blood, tissue and/or other specimens? If so, you may be eligible to participate in a study to help develop new products such as microbicides or vaccines which may help prevent HIV, HPV or other sexually transmitted diseases. No products are tested in or on participants. Compensation is provided.

ACTG A5294 BIRTH PRO12010297
Are you at least 18 years of age? Do you have HIV and Hepatitis C (HCV)? If so, and if your HIV viral load is less than 50,000 and your CD4 count is more than 200, you may be eligible to participate in a study to see if adding a new drug to standard anti-HCV treatment is safe and whether it will help people with both HIV and HCV better fight their HCV. Travel-related costs reimbursed.

ACTG A5298 PRO11090510
Are you a HIV-infected man who has sex with other men and are aged 27 years or older? If so, you may be eligible to participate in a study to determine the acceptability of procedures and treatments associated with anal HPV infection. The participants in this study will have anal HPV DNA testing, oral HPV DNA testing, high-resolution anoscopies and other tests. Travel costs will be reimbursed.

ACTG A5258 PRO10120420
Are you a HIV infected man or woman between the ages of 18 and 65 years old? If so, you may be eligible to participate in a study to learn how well chloroquine, a medication approved by the FDA to treat malaria, reduces the level of activated CD8 T cells. Increased activation of CD8 T cells has been associated with progression of HIV disease. This study will take up about 28 weeks to complete.

To find out about the Research Participant Registry and opportunities to participate in research studies (or to withdraw from the Registry), contact researchregistry@hs.pitt.edu or call 1-866-438-8230.
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Last Update June 2014