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Healthy Volunteer Studies


Listed below are several healthy volunteer studies that are currently recruiting through the Research Participant Registry. If you are interested in hearing more about one or more of the studies listed below, please contact the Research Participant Registry at 1-866-438-8230 or via e-mail researchregistry@hs.pitt.edu.

Ankle Injury Study – Healthy Volunteer University of Pittsburgh PRO16010581B
Are you a club level soccer player between the ages of 18-35 who has never had an ankle sprain? If so, you may be eligible for a study to help researchers develop programs that aim to decrease the risk of ankle sprains. Participation involves one 2-hour testing session. Monetary compensation and a body composition analysis to measure your body fat percentage are provided.

Impact of Sleep on Chronobiology of Micturition University of Pittsburgh PRO16030229
Are you a relatively healthy adult age 60 and older? If so, you may be eligible to participate in a study to help researchers improve their understanding of the impact of sleep on nighttime urine production. Participation involves a screening visit, two 24-hour study visits scheduled 6 weeks apart, and follow-up phone calls. Participants will be compensated.

Adult Participants Needed for a Childhood Experiences and the Brain Study University of Pittsburgh PRO14060090
Are you between 21 and 35 years old? Did you have a difficult childhood? If so, you may be eligible to participate in a study examining how difficult childhood experiences can change stress pathways in the brain and how these changes may influence stress responses and mental health in adulthood. Study involves 2 visits totaling approximately 4-6 hours including an MRI scan. Compensation provided.

Brain Imaging Study for Healthy Volunteers University of Pittsburgh PRO13120161B
Are you a relatively healthy postmenopausal woman between 60-75 years old? If so, you may be eligible to participate in a study to help researchers understand the way the brain works in women with breast cancer who take aromatase inhibitors compared to healthy women. Study involves two visits where you will perform tasks in a MRI scanner. Participants will be compensated./td>

Seasonality Study-Healthy Volunteers University of Pittsburgh PRO08100337A
Seeking healthy individuals between 36 and 65 years old who have never experienced depression. The purpose of this study is to investigate the effects of environmental light from the sun and lamps in our homes and offices on our moods, energy level, and sleep. Total participation involves six visits across a year, and compensation is provided.

The Impact of Social Ties on Health Disparities Using Social Media Streams University of Pittsburgh PRO15080005
Are you an active twitter user? If so, you may be eligible to participate in this study to see if twitter feeds can be used to help understand population health. Participation will last 30-60 days, and involves taking two on-line surveys and allowing the researcher to collect your twitter activity. You may also be invited to participate in an in-person follow-up interview. Compensation provided.

CMU SMART Study Carnegie Mellon University HS15-113
Are you an adult who is in generally good mental and physical health, but who is feeling stressed? Do you own a smartphone? If so, you may be eligible to participate in an eight-week training program for stress reduction and well-being. Participants must be available for about 10 weeks to complete study activities and training. Compensation provided.

Emotion Regulation in Depression – Healthy Volunteers University of Pittsburgh PRO12110325B
Researchers at UPMC are conducting a study that focuses on the functional brain images of men between the ages of 25 and 40 who are experiencing an episode of depression and how they differ from those with no history of any disorders. You may qualify if you have no personal or family history of psychiatric disorders, and are right-handed. Compensation provided.

AAPECS Study – Healthy Volunteers University of Pittsburgh PRO15120131A
Researchers at the University of Pittsburgh are looking for adults between the ages of 18-40 to answer questions about common experiences in daily life. Eligible participants will use a study-provided smartphone to answer daily questionnaires about their social interactions, emotions, and stressful events. Compensation provided.

MR spectroscopic imaging of epilepsy – healthy volunteers University of Pittsburgh PRO13030356B
Are you a relatively healthy non-smoking adult between 40-65 years old? If so, you may be eligible to participate in a study to help researchers measure the chemical composition of different brain regions using MRI scanning. Up to 3 study visits are possible, with each visit lasting about 1.5 hours. At any given visit, up to two MRI scans may be performed. Compensation provided.

Enroll-HD University of Pittsburgh PRO12050002
Researchers are collecting data from families in an effort to improve their understanding and treatment of Huntington’s disease (HD). Any member of a family affected by HD can take part, including those who are gene negative, gene unknown, and gene positive. Those who have a family history of HD, as well as spouses, caregivers and family members of those with HD are also invited to participate.

ENT Research Fly - Healthy Adults University of Pittsburgh PRO13040671E
Are you age 19 OR between ages 30-50 and do you travel frequently in an airplane without having ear pain or problems? If so you may be eligible to participate in a study to help determine if new tests of Eustachian tube function can identify persons who will experience ear pain/problems when exposed to rapid changes in air pressure. Involves one study visit. Compensation provided.

Sleep and Cognition Study University of Pittsburgh PRO14010270
Are you 50 or older? Do you have trouble staying asleep at night? If so, you may be eligible to participate in a study to see how sleep benefits cognition and brain function. Participation involves two sleep studies, cognitive tests, and MRI scans. The entire study duration is 17 days. Compensation provided.

AgileLife PTS Focus Group University of Pittsburgh PRO15100238
Do you have at least two years of experience with patient transfer and transport? Are you currently, or were you recently (within the past 2 years), employed as a rehabilitation professional? If so, you may be eligible to participate in a study to help evaluate the AgileLife Patient Transfer System (PTS). Study involves 1 in-person visit lasting up to 3 hours. Compensation provided.

Brain Study University of Pittsburgh PRO15070055A
Are you a man who is either age 19, 23, or 30 years old OR are you a women who is either age 18 or 29 years old? If so, you may be eligible to participate in a study to learn more about how the brain develops. The study involves questionnaires, computer games, and brain scans completed during one 2-hour session and one 5-hour session at our laboratory and at UPMC Presbyterian Hospital. Compensation and parking provided.

FACE-PC: Family Caregivers University of Pittsburgh PRO14040546B
Do you help to take care of a loved one who has multiple medical conditions and depression? If so, you may be eligible to participate in a study to help older adults with depression and chronic medical conditions and their loved ones manage their health. Participants must have at least twice weekly contact with their family member for a minimum of 4 hours. Compensation provided.

PDE10a Imaging in Cocaine Use Disorders – Healthy Volunteers Needed University of Pittsburgh PRO15120245A
Healthy men and women between 18-50 years of age needed for a brain imaging study! Participants must be prescription medication free (birth control acceptable). Participation involves questionnaires, interviews and brain scanning at UPMC Presbyterian. Brain scanning includes 1 MRI, 1 CT, and 1 PET scan. Study participation will last 3 days. Compensation provided.

SFeRe Study PRO11010529
Do you sleep well? Researchers at the University of Pittsburgh are enrolling healthy men and women between the ages of 18 and 30 for an on-campus research study. Study involves 2 in person evaluations, 3 in lab sleep studies, and 4 MRIs. Compensation and parking provided.

MyPaTH Story Booth University of Pittsburgh PRO15100466
Volunteers are needed to share a story about their experience as a patient or their experience providing care for someone else who is ill. Participation will involve a one-on-one interview with a friend, family member, caretaker, or research staff member and completing a brief questionnaire. The interview will last up to 20 minutes and will be audio-recorded.

The Vacation Study University of Pittsburgh PRO15060504
Are you an adult HIV-uninfected, gay/bi male (born male) who is planning to take a vacation in the next few months? Have you had unprotected anal sex in the past year? If so, you may be eligible to participate in a study to help investigators test the feasibility and acceptability of short-term PrEP. PrEP can reduce the risk of HIV-infection in HIV-uninfected gay/bi men. Compensation provided.

The ENRGISE Study University of Pittsburgh PRO15060563
Are you age 70 or older and having difficulty walking several blocks or climbing a flight of steps? If so, you may be eligible to participate in a study to test if study medications will reduce the level of inflammation in your blood and see if this improves mobility and function. Participation will last about 12 months. Compensation provided.

Impact of Labor Pain on Postpartum Depression and Psychosocial Health (LPPD) Study University of Pittsburgh PRO15030338
Are you pregnant now, in your 3rd trimester, and have you never been through childbirth? If so, you and your future infant may be eligible to participate in a study on the impact of labor pain and postpartum depression. Participation involves 5 encounters over 3 months. Participants will be compensated.

Bunion Study – Healthy Volunteers University of Pittsburgh PRO15060322
Are you a woman between the ages of 30-65 with normal feet? If so, you may be eligible to participate in a study to help researchers analyze and compare CT and x-ray images and bone quality from patients diagnosed with bunions to those without bunions. This study involves one in-person visit lasting about 1 hour at UPMC Passavant. Free parking provided.

The Indian Healthy Relationships Study University of Pittsburgh PRO15080066
Are you a Hindu Asian Indian-born woman who is a U.S. citizen and lives in Allegheny County or surrounding counties? If so, you may be eligible to participate in a study to help investigators understand how women think about, experience, and respond to conflict in relationships. Participation involves completing several surveys and an interview. Compensation provided.

Childhood Cavity Study – Pregnant Women Needed! University of Pittsburgh PRO09090132
Are you Caucasian and in your first or second trimester of pregnancy? Are you healthy enough to undergo a dental exam? If so, you may be eligible to participate in a study to help researchers investigate the early development of childhood cavities. Study participation involves several interviews and visits for you and your baby. Participants will be compensated.

Characteristics of Active Smokers Carnegie Mellon University HS15-413
Are you a cigarette smoker who is between the ages of 18-50 years old? If so, you may be eligible to participate in a study to help researchers understand the characteristics of smokers. Study involves two visits on the Carnegie Mellon University campus. Must be willing to not smoke or use nicotine products before one session. Compensation is provided.

Acculturation of Arab-American Women University of Pittsburgh PRO15100191
Researchers are interested in exploring how Arab-American women adjust to culture in the United States. Eligible participants for this study are Arab-American women (with two Arab parents) of any generational group (1st, 2nd or more) who have been living in the U.S. and are married to an Arab spouse, or are divorced from an Arab spouse, or are living/have lived with an Arab male partner.

WiseSOVA Study University of Pittsburgh PRO15060158C
Are you the parent of a teen or young adult between the ages of 14-26 who has symptoms of depression or anxiety? If so, you may be able to participate in a study to help design an educational website by contributing feedback, advice and experiences to share with other parents who have been through similar experiences. This study is done entirely online. Compensation provided.

Behavioral Assessment Survey University of Pittsburgh PRO15110133
Healthy participants are needed to complete a short online survey to help researchers understand certain emotions and behaviors among adults. Participants must be fluent in English with NO history of brain injury or neurological condition. The survey will take about 10-15 minutes to complete. Participants can elect to be entered into a raffle to win a gift card.

Orofacial Cleft Family Study– Healthy Volunteers University of Pittsburgh IRB0607057B
The Center for Craniofacial and Dental Genetics is recruiting children and adults to participate in a study examining the genetic factors contributing to cleft lip and cleft palate. We are recruiting healthy individuals who are either Caucasian of European descent, Asian, and/or Hispanic of both sexes aged 5 to 110, WITHOUT a personal history of cleft lip and/or cleft palate.

EpiPrEP Pitt Pilot Study University of Pittsburgh PRO15010326
Are you a HIV-negative man who has sex with other men? Are you planning on going away on vacation soon? If so, you may be eligible to participate in a study to help investigators test the feasibility and acceptability of short-term PrEP. PrEP is taking medications typically used to treat HIV to help prevent HIV. Compensation provided.

WELL Study: Promoting Widowed Elders Lifestyle after Loss University of Pittsburgh PRO14110233
Are you 60 years of age or older? Did your spouse or partner pass away within the past 6 months? If so, you may be eligible to participate in a study to help researchers learn about older adults’ health behaviors after they lose their spouse or partner. Participation will last up to 12 months. Compensation provided.

RAD Study – Healthy Volunteers University of Pittsburgh PRO15010521D
Are you 18 years of age and have no history of or current mental illness or drug and alcohol dependence? If so, you may be eligible to participate in a study about the functioning of the brain and thinking processes. Participation involves psychiatric assessments, paper and pencil testing and EEG. Compensation provided.

Smart Phone Apps Study for Caregivers University of Pittsburgh PRO14120443C
Are you the primary caregiver of an individual with a diagnosis of Spina Bifida, Spinal Cord Injury, Traumatic Brain Injury, or Cerebral Palsy? If so, you may be eligible to participate in group discussions with other caregivers on how to best support and prepare individuals with disabilities and chronic disorders to take better care of themselves using technology. Compensation provided.

Sleep, Circadian Rhythms & Cardiometabolic Risk in Retired Shift Workers University of Pittsburgh PRO14120523A
Researchers are conducting a study to learn more about how sleep, health and functioning are affected by former years of shift work. Eligible participants are age 60 and older and have retired from a job which involved work at night (after midnight) on either a permanent or rotating basis. Compensation provided.

Sleep, Circadian Rhythms & Cardiometabolic Risk in Retired Shift Workers – Retired Day Workers Needed University of Pittsburgh PRO14120523B
Researchers are conducting a study to learn more about how sleep, health and functioning are affected by former years of shift work. Eligible participants are age 60 and older and have retired from a job which did NOT involve work at night (after midnight) on either a permanent or rotating basis. Compensation provided.

The ASSET Study – Age 18 without a family history of mental illness University of Pittsburgh PRO13070299D
Are you 18 years of age and without a family history of mental disorders? If so, you may be eligible to participate in a study to help further the understanding of social cognition and the effects of daily stressors. Teens must have no diagnosis of mental health or substance abuse issues. Involves 4 sessions held in Oakland. A parent must participate, too. Compensation provided.

Oral Microbiome and Digestive Studies PRO12070179
Are you interested in getting a dental X-ray? If so, you may be eligible to participate in a study to test if periodontal disease is connected to a variety of other diseases, including inflammatory bowel disease, heart disease, etc. Study involves one hour long visit. Study procedures include getting a panoramic radiograph (x-ray) taken, undergoing a brief gum exam, and providing some saliva.

Alzheimer’s Disease Research Center – Healthy Volunteers Needed! University of Pittsburgh IRB950783A
Are you age 60 and older? Do you have a “study partner” who can accompany you to clinic visits? If so, you may be eligible to participate in a study to help researchers identify memory problems at the earliest stages of Alzheimer’s disease. Participants will receive a physical exam, a review of medications, and paper and pencil memory testing. Parking provided.

Gestational Diabetes Diagnostic Methods Study (GDM² Study) University of Pittsburgh PRO14070556
Are you less than 24 weeks pregnant and planning to have your baby at Magee Womens Hospital? If so, you may be eligible to participate in a study to see which of the two ways to test for diabetes during pregnancy results in more healthy deliveries for mom and baby. Participants must NOT have diabetes, take high blood pressure medication, or be expecting more than one baby. Compensation provided.

LoNIC Study University of Pittsburgh PRO13070454
Are you at least 21 years old and do you smoke cigarettes, but only on some days (not every day)? Are you interested in trying research cigarettes? If so, you may be eligible to participate in a study that is investigating the impact of different nicotine levels in cigarettes. Evening study appointments available. This is NOT a treatment program for smoking. Compensation provided.

QUITS Study University of Pittsburgh PRO12070152
Are you at least 21 years old and do you smoke cigarettes, but only on some days (not every day)? Are you interested in trying to quit smoking? If so, you may be eligible to participate in a study to help researchers understand the process and challenges of quitting smoking experienced by non-daily smokers so that strategies for successful smoking cessation may be developed. Evening study appointments available. Compensation provided.

Characteristics and Experiences of Current Smokers University of Pittsburgh PRO13110547
Are you a current smoker who is between the ages of 18-55 years old and speaks fluent English? If so, you may be eligible for a study interested in learning more about the characteristics and experiences of current smokers. Participation involves 1 screening visit and 2 study visits. Participants must be willing to not smoke for 8 hours before the 2 study visits. Compensation provided.

Healthy Brain Research Study University of Pittsburgh PRO14070229
Are you an adult who does NOT exercise regularly and who is between the ages of 75 and 85 years old? Are you able to safely participate in moderate intensity exercise? If so, you may be eligible to participate in a study to examine the effect of physical activity on brain health, cognitive tasks, and measures of cardiovascular health. Study will last 6 months. Compensation provided.

Biomarkers in the HPA axis for depression and posttraumatic stress disorder - healthy volunteers PRO13100367A
Are you a relatively healthy married adult with or without dependent children? If so, you may be eligible to participate in a study to learn more about biological factors related to depression and posttraumatic stress disorder in adults. This study involves 2 visits, six months apart. Participants will be compensated.

CHIC II Study PRO11120183
Are you a generally healthy woman between the ages of 18 and 34 years old who has regular periods? If so, and if you are not pregnant or currently using hormones for birth control, you may be eligible to participate in a study to better understand how birth control affects the immune cells within the reproductive tract. Compensation is provided.

POF Study – Healthy Controls PRO09080427
Are you a woman who has reached (or will reach) menopause after the age of 46? Do you have at least 1 live born child? Or have you chosen not to have children due to personal and not medical reasons? If so, you may be eligible for a study to learn more about the genetics of Premature Ovarian Insufficiency (POI). POI causes premature menopause and infertility. There is one study visit at Magee.

HIV Prevention Research Registry PRO11110371
Are you interested in learning about HIV prevention research studies taking place at the University of Pittsburgh and UPMC? If so, you can join the HIV Prevention Research Registry. HIV prevention registry members may be contacted by registry staff members about studies for which they appear to qualify. Eligible participants are ages 18 and older.

Communal Health Interactions in Couples Study (CHOICES) PRO12070370
A CMU/Pitt couples research study is looking for couples (married or living together for at least 2 years) with one partner diagnosed with Type 2 diabetes in the past two years (spouse/partner does NOT have diabetes). Study involves interviews, conversations and answering questions about diabetes. Study location is flexible. Participants will be compensated.

TrialNet-Pathway to Prevention - Age 18-45 PRO10080594A
Are you between the ages of 18 and 45, with a relative who has Type 1 diabetes (T1D)? If so, you may be eligible to be screened for T1D studies, with the goal of preventing T1D in the future. With a blood test, doctors can determine if an individual is at risk for T1D years before symptoms occur. Those at increased risk for T1D may be eligible to join studies that may prevent or delay T1D.

Venous Genetic Study - Healthy Volunteers PRO10120155
Are you a relatively healthy adult age 50 or older who does not have varicose veins and is not taking steroids (i.e., prednisone)? If so, you may be eligible to participate in a genetic study about vein disease. Study involves a medical history, a review of your circulatory function, one blood draw, a free meal ticket and a free15 minute vein ultrasound exam of both legs.

To find out about the Research Participant Registry and opportunities to participate in research studies (or to withdraw from the Registry),
contact researchregistry@hs.pitt.edu or call 1-866-438-8230.
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