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Healthy Volunteer Studies


Listed below are several healthy volunteer studies that are currently recruiting through the Research Participant Registry. If you are interested in hearing more about one or more of the studies listed below, please contact the Research Participant Registry at 1-866-438-8230 or via e-mail researchregistry@hs.pitt.edu.

Health Valuation Study University of Pittsburgh PRO14110193
Are you an adult age 18 or older who is comfortable communicating with others in English? If so, you may be eligible to participate in a study to help researchers understand how the general public values health-related quality of life. Study involves an interview to compare different descriptions of health. This interview will be video recorded. Only one study visit. Compensation provided.

ONTX + HF Study – Healthy Volunteers University of Pittsburgh PRO15020481B
Men and women age 75 and older are need for a study to help researchers better understand how nitrite therapy impacts skeletal muscle, functional capacity and quality of life. Study involves 5 outpatient visits over 3 months. Compensation and parking provided.

Depression Research Study - Healthy Volunteers University of Pittsburgh PRO14080281B
Are you age 21 or older and have NO psychiatric history? If so, you may be eligible to participate in a study to help researchers understand why some people become depressed and have thoughts of hurting themselves, while others do not. This study involves 2-3 sessions totaling between 3-6 hours. Participants will be compensated.

The ASSET Study – Age 18 or 19 without a family history of mental illness University of Pittsburgh PRO13070299D
Are you either 18 or 19 years of age and without a family history of mental disorders? If so, you may be eligible to participate in a study to help further the understanding of social cognition and the effects of daily stressors. Teens must have no diagnosis of mental health or substance abuse issues. Involves 4 sessions held in Oakland. A parent must participate, too. Compensation provided.

Orofacial Cleft Family Study– Healthy Volunteers University of Pittsburgh IRB0607057B
The Center for Craniofacial and Dental Genetics is recruiting children and adults to participate in a study examining the genetic factors contributing to cleft lip and cleft palate. We are recruiting healthy Caucasian individuals of European descent of both sexes aged 5 to 110, WITHOUT a personal history of cleft lip and/or cleft palate or genetic syndromes to participate.

Working Memory Study University of Pittsburgh PRO15030191
Are you between the ages of 40-85 years old with at least an eighth grade education and did you learn only English in childhood? If so, you may be eligible to participate in a study that is examining the relationship between working memory capacity for language and the ability to interpret text. Study involves one visit that will take approximately 90 minutes to complete. Parking reimbursed.

Sedation – Memory Study University of Pittsburgh PRO14050609
Researchers are recruiting healthy native English-speaking adults between the ages of 18-40 for a study to better determine the effect that anesthetic agents have on memory formation during the experience of pain. The study is split into 2 parts, and each part involves 3 visits to UPMC Presbyterian, separated by 1-3 days each. Participants will be compensated.

ICU StoryWeb Study University of Pittsburgh PRO15030503
Have you participated in a decision to limit life-sustaining treatment for a family member or friend in the intensive care unit (ICU)? If so, you may be eligible to participate in a study to help researchers develop a website that will allow people who have had a similar experience to listen to others’ stories, share their own story, and connect to helpful resources. Compensation provided.

Brain Study for Healthy Adults University of Pittsburgh PRO12040555
Are you between the ages of 40-60 years old and right-handed? If so, you may be eligible to participate in a study to help researchers understand how differences in metabolism are related to brain responses to rewarding tastes. Understanding these differences may help us understand how the brain contributes to obesity and diabetes. Compensation and parking are provided for each study visit.

ENT Research – Healthy Volunteers PRO13040386B
Are you a healthy adult between the ages of 18 and 50? If so, you may be eligible to participate in a study to determine if allergic rhinitis (nasal allergy) increases the rate of blood-flow in the lining of the middle ear. Participants must have no chronic conditions or any known allergies. This study requires two visits to Children’s Hospital of Pittsburgh. Compensation provided.

Oral Microbiome and Digestive Studies PRO12070179
If you are at least 18 years of age and do NOT have inflammatory bowel disease (IBD), you may be eligible to participate in a study to test if the types of bacteria in the mouth influence inflammatory bowel disease. Participants will visit the Dental CTRC in Salk Hall for a one hour study visit to have a panoramic radiograph (x-ray) taken, undergo a brief gum exam, and provide some saliva.

CMU Hunger Study Carnegie Mellon University HS15-344
Are you between 18-30 years old, free from food allergies, and in good physical health? If so, you may be eligible to participate in a study to help researchers understand people’s hunger levels. Study involves 1 in-person study visit that will last about 1 hour. Participant must be willing to NOT eat for at least 4 hours before study visit. Compensation provided.

Alzheimer’s Disease Research Center – Healthy Volunteers Needed! University of Pittsburgh IRB950783A
Are you age 60 and older? Do you have a “study partner” who can accompany you to clinic visits? If so, you may be eligible to participate in a study to help researchers identify memory problems at the earliest stages of Alzheimer’s disease. Participants will receive a physical exam, a review of medications, and paper and pencil memory testing. Parking provided.

Gestational Diabetes Diagnostic Methods Study (GDM² Study) University of Pittsburgh PRO14070556
Are you less than 24 weeks pregnant and planning to have your baby at Magee Womens Hospital? If so, you may be eligible to participate in a study to see which of the two ways to test for diabetes during pregnancy results in more healthy deliveries for mom and baby. Participants must NOT have diabetes, take high blood pressure medication, or be expecting more than one baby. Compensation provided.

MTN-027 Ring Study University of Pittsburgh PRO15020053
Researchers are looking for volunteers who want to participate in a safety study of a vaginal ring to prevent HIV. Eligible participants are healthy, HIV-negative, and between the ages of 18-45 years old. Participants must be willing to be sexually abstinent during study participation and must not be at risk for pregnancy. Involves 13 offices visits over 5 weeks. Compensation provided.

LoNIC Study University of Pittsburgh PRO13070454
Are you at least 21 years old and do you smoke cigarettes, but only on some days (not every day)? Are you interested in trying research cigarettes? If so, you may be eligible to participate in a study that is investigating the impact of different nicotine levels in cigarettes. This is NOT a treatment program for smoking. Compensation provided.

QUITS Study University of Pittsburgh PRO12070152
Are you at least 21 years old and do you smoke cigarettes, but only on some days (not every day)? Are you interested in trying to quit smoking? If so, you may be eligible to participate in a study to help researchers understand the process and challenges of quitting smoking experienced by non-daily smokers so that strategies for successful smoking cessation may be developed. Compensation provided.

Smartphone Stress Reduction Study Carnegie Mellon University HS15-005
Stressed? Interested in learning techniques to manage your stress? If so, you may be eligible to participate in a study testing a two-week at-home training program for stress reduction and well-being. Participants must be between the ages of 18-70, own a smartphone, and be in good physical and mental health. The study will take about one month to complete. Compensation provided.

Characteristics and Experiences of Current Smokers University of Pittsburgh PRO13110547
Are you a current smoker who is between the ages of 18-55 years old and speaks fluent English? If so, you may be eligible for a study interested in learning more about the characteristics and experiences of current smokers. Participation involves 1 screening visit and 2 study visits. Participants must be willing to not smoke for 8 hours before the 2 study visits. Compensation provided.

The Couples Study University of Pittsburgh PRO12030125
Researchers are conducting a study to help determine the relationship between particular personality traits, emotion, and how individuals interact with people close to them. Eligible participants are between ages 18-40, are married or in a romantic relationship, and at least one partner in the relationship is currently receiving mental health treatment. Compensation provided.

Smoking Cessation Study University of Pittsburgh PRO14100229
Do you want to quit smoking in 2015? If so, you may be eligible to participate in a study to help researchers determine the effectiveness of a text messaging program aimed at helping adult smokers quit. Participants are between ages 18-30, smoke cigarettes every day, want to quit smoking, and use a mobile phone that can receive text messages. Study will last about 6 weeks. Compensation provided.

Smoking Study University of Pittsburgh PRO14030573
Relatively healthy smokers who want to try new cigarettes that may or may not lead to reduced smoking are wanted for a research study. This is NOT a treatment or smoking cessation study. Involves 10 in-person study visits. Evening study appointments available. Compensation provided.

ENT Research Fly/Dive Healthy Adults University of Pittsburgh PRO13040671E
Are you between the ages of 18-50 years old and do you scuba dive or travel frequently in an airplane without having ear pain or problems? If so you may be eligible to participate in a study to help determine if new tests of Eustachian tube function can identify persons who will experience ear pain/problems when exposed to rapid changes in air pressure. One visit. Compensation provided.

Social stressors, air pollution, and cancer in Allegheny County University of Pittsburgh PRO14070250
Do you live in Hazelwood-Glenfield? If so, you may be eligible to participate in a focus group to help researchers understand how neighborhood stressors may differ across the city of Pittsburgh, and how they may be related to environmental pollution and health. Compensation provided.

Sleep in Relation to Positive/Negative Affect Systems (SIRA) University of Pittsburgh PRO14040026
Are you right-handed and between the ages of 18-30? If so, you may be eligible for a study to help researchers understand how sleep relates to the way your brain controls emotion, or affect. Study involves interviews, questionnaires, diaries, actigraphy, and functional magnetic resonance imaging (fMRI) studies. Compensation provided.

Healthy Brain Research Study University of Pittsburgh PRO14070229
Are you an adult who does NOT exercise regularly and who is between the ages of 65 and 85 years old? Are you able to safely participate in moderate intensity exercise? If so, you may be eligible to participate in a study to examine the effect of physical activity on brain health, cognitive tasks, and measures of cardiovascular health. Study will last 6 months. Compensation provided.

ROSE Study University of Pittsburgh PRO14070387
Researchers at the University of Pittsburgh are looking for volunteers to participate in ROSE, a study designed to help them understand what is most important to midlife women’s sexual satisfaction. Eligible participants are between the ages of 45 and 60, and have been sexually active in the past 12 months. Study involves a 1-2 hour interview or focus group. Participants will be compensated.

My Life Check Study University of Pittsburgh PRO14030656
Are you an overweight or obese adult between the ages of 18 and 35? If so, you may be eligible to participate in a study to examine if an intervention based on the American Heart Association’s My Life Check website can help adults improve their dietary and physical activity habits. Must have phone and Internet access. Participation will last up to 12 weeks. Compensation provided.

Pulmonary Study - African American Men and Women Ages 35-65 University of Pittsburgh PRO10060177
African American men and women between the ages of 35 and 65 years old needed for lung function study. Participants will complete a questionnaire, participate in pulmonary function testing, provide a blood specimen, provide a sputum specimen, and have fat tissue biopsied (optional). Men must be current or former smokers and women must be currently smoking. Compensation provided.

Communication Research Study – Healthy Volunteers University of Pittsburgh PRO11120221B
Are you a native English speaker who is between the ages of 50 and 85 years old? If so, you may be eligible to participate in a study on how people understand sentences. Participation consists of either one or two sessions lasting between one and two hours, and, if eligible, a neuroimaging session. Compensation provided.

UPMC Brain Development Study - Ages 18-30 University of Pittsburgh PRO10090478B
Are you relatively healthy and between the ages of 18-30? If so, you may be eligible to participate in a study to learn more about how the brain develops. The study involves questionnaires, computer games, and brain scans completed during three 2-hour sessions at our laboratory and at UPMC Presbyterian Hospital. Participants will be compensated. Parking is provided.

Glasses Study University of Pittsburgh PRO14050289
Are you between the ages of 40 and 50 and do you plan to start wearing progressive lens glasses for the first time OR are you between the ages of 70 and 80 and you have been wearing progressive lens glasses for at least 1 year? If so, you may be eligible to participate in a study looking at the effects of progressive lens glasses on balance. Involves 2-3 visits. Compensation provided.

Genetics of Inflammatory Bowel Disease – Healthy Volunteers University of Pittsburgh IRB0503185
Are you a healthy, white individual between the ages of 18 and 35? If so, you may be eligible to help researchers understand the genetics of inflammatory bowel disease (IBD). Researchers hope to identify IBD-causing genes, which determine a person’s make-up and inherited traits. Involves one study visit, participants will be asked to give approximately 4 tbsp. of blood. Compensation provided.

Military Couples Sleep Study PRO11040328
Researchers are investigating how sleep affects relationships and health in military couples. Participants must be between 18-50 years old, married or living together and at least one member of the couple must have served in OEF/OIF/OND. Both members must be willing to participate. Compensation and parking provided.

Biomarkers in the HPA axis for depression and posttraumatic stress disorder - healthy volunteers PRO13100367A
Are you a relatively healthy married adult with or without dependent children? If so, you may be eligible to participate in a study to learn more about biological factors related to depression and posttraumatic stress disorder in adults. This study involves 2 visits, six months apart. Participants will be compensated.

Insomnia and Cardiovascular Health Study – Healthy Volunteers PRO13070559B
Are you a good sleeper? If so, and if you are you between the ages of 18 and 50, you may be eligible to participate in a study to help better understand the relationship between sleep and cardiovascular risk in adults with insomnia versus those without insomnia. Participation involves 3 study visits, including one overnight sleep and heart health assessment. Compensation is provided.

Family Caregiving Video Study PRO11050668
This study explores how family caregivers deal with behaviors associated with memory loss. A wearable camera system captures daily interaction between family caregivers and persons with memory loss, as a basis for discussion of new ways of handling difficult behaviors. All study activities take place in participants’ homes, and at participants’ convenience. Compensation is provided.

ENT Research – Ragweed Study PRO13040368A
Do you have ragweed allergy? Are you a relatively healthy adult between the ages of 18 and 50? If so, you may be eligible to participate in a study to determine if allergic rhinitis (nasal allergy) increases the rate of blood-flow in the lining of the middle ear. This study requires three visits to Children’s Hospital of Pittsburgh. Compensation provided.

CHIC II Study PRO11120183
Are you a generally healthy woman between the ages of 18 and 34 years old who has regular periods? If so, and if you are not pregnant or currently using hormones for birth control, you may be eligible to participate in a study to better understand how birth control affects the immune cells within the reproductive tract. Compensation is provided.

SFeRe Study PRO11010529
Do you sleep well? Researchers at the University of Pittsburgh are enrolling healthy men and women between the ages of 18 and 30 for an on-campus research study. Study involves 2 in person evaluations, 3 in lab sleep studies, and 4 MRIs. Compensation and parking provided.

POF Study – Healthy Controls PRO09080427
Are you a woman who has reached (or will reach) menopause after the age of 46? Do you have at least 1 live born child? Or have you chosen not to have children due to personal and not medical reasons? If so, you may be eligible for a study to learn more about the genetics of Premature Ovarian Insufficiency (POI). POI causes premature menopause and infertility. There is one study visit at Magee.

HIV Prevention Research Registry PRO11110371
Are you interested in learning about HIV prevention research studies taking place at the University of Pittsburgh and UPMC? If so, you can join the HIV Prevention Research Registry. HIV prevention registry members may be contacted by registry staff members about studies for which they appear to qualify. Eligible participants are ages 18 and older.

Communal Health Interactions in Couples Study (CHOICES) PRO12070370
A CMU/Pitt couples research study is looking for couples (married or living together for at least 2 years) with one partner diagnosed with Type 2 diabetes in the past two years (spouse/partner does NOT have diabetes). Study involves interviews, conversations and answering questions about diabetes. Study location is flexible. Participants will be compensated.

TrialNet-Pathway to Prevention - Age 18-45 PRO10080594A
Are you between the ages of 18 and 45, with a relative who has Type 1 diabetes (T1D)? If so, you may be eligible to be screened for T1D studies, with the goal of preventing T1D in the future. With a blood test, doctors can determine if an individual is at risk for T1D years before symptoms occur. Those at increased risk for T1D may be eligible to join studies that may prevent or delay T1D.

WEPOD Study PRO12030433
Are you a woman with a diagnosis of epilepsy between the ages of 18-40 who is planning to get pregnant? If so, you may be eligible to participate in a study to help researchers evaluate if it is more difficult for women with epilepsy to become pregnant than healthy women without epilepsy, and to compare seizure frequency in women with epilepsy before and during pregnancy. Compensation provided.

Venous Genetic Study - Healthy Volunteers PRO10120155
Are you a relatively healthy adult age 50 or older who does not have varicose veins and is not taking steroids (i.e., prednisone)? If so, you may be eligible to participate in a genetic study about vein disease. Study involves a medical history, a review of your circulatory function, one blood draw, a free meal ticket and a free15 minute vein ultrasound exam of both legs.

Imaging of Cortical Dopamine Transmission in Alcohol Dependence – Healthy Smokers PRO08070098B
Healthy smokers needed for brain imaging study. Are you a man or a woman between the ages of 18 and 40 years old? Do you smoke? If so, you may be eligible to participate in this study which involves questionnaires, interviews and brain scanning (1-MRI, 2-PET scans). Participants must be medication-free (birth control acceptable). Compensation provided.

Imaging of Cortical Dopamine Transmission in Alcohol Dependence PRO08070098A
Are you a man or a woman between the ages of 18 and 40 years old? Do you currently have, or have you had in the past, a problem with alcohol? If so, you may be eligible to participate in this brain imaging research study. This study involves questionnaires, interviews and brain scanning (1-MRI, 2-PET scans). Participants must be medication-free (birth control acceptable). Compensation provided.

To find out about the Research Participant Registry and opportunities to participate in research studies (or to withdraw from the Registry),
contact researchregistry@hs.pitt.edu or call 1-866-438-8230.
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